BCHM 307 Biochemistry
CRN: 27331


About the Course

This is an 8-week course offered in the summer. Students who enroll in BCHM 30700 have wide-ranging interests and aspire to pursue careers in biological or life sciences and engineering, medicine, pharmacy, nursing, veterinary medicine, animal science, dietetics, food science, nutrition, botany and plant sciences, and chemical engineering. This course will provide students with the basic foundation of biochemistry concepts that will be required for the pursuit of their academic and career objectives. The first third of the course will use a structure-based approach to introduce students to central biomolecules including nucleic acids, proteins, carbohydrates, and lipids. As each biomolecule is described, its relevance and context will be demonstrated using real-world examples drawn from human health and agriculture. This part of the course will cover the molecular basis of protein structure and the catalytic activity of enzymes. During the second third of the course, the essential features of the central dogma will be described with an emphasis on the enzymes and macromolecules that are involved in replication, transcription and translation. The final third of the course will cover central metabolic pathways and focus on the interconnection between glycolysis, the citric acid cycle and the production of chemical energy by the formation of proton gradients, and photosynthesis.

Course Goals

Upon completion of BCHM 30700, students with a passing or above grade will be able to:

  • Examine the structure/function relationship of biological macromolecules.
  • Outline the central dogma of molecular biology.
  • Describe intermediary carbon metabolism: glycolysis, the citric acid cycle, oxidative phosphorylation and photosynthesis.
  • Critique case studies and articles that discuss the contributions of biochemistry to society, including improvements to medicine agriculture and the economy.

Learning Resources

Textbook

Essential Biochemistry, Third Edition by Pratt and Cornely. Published by John Wiley & Sons, Inc. Online access to WileyPlus recommended.

SUGGESTED VERSIONS ISBN
Hardcover Text with WileyPLUS 9781118567883
Loose-leaf, binder-ready text with WileyPLUS 9781118567715
E-text with WileyPLUS 9781118567586

A webcam will be required for taking quizzes and exams.

Access to general movies and/or tv shows will be required for the group project.

Course Syllabus

Content Areas
Level 1 Level 2 Level 3
Introduction to Biochemistry Introduction to Biochemistry Introduction to Biochemistry
Aqueous Chemistry
From Genes to Proteins
Protein Structure Protein structure and function Strucure and function of biological macromolecules
Protein Function
How Enzymes Work Enzyme function and inhibition
Enzyme Kinetics and Inhibition
Lipids and Membranes Lipids and Membranes
Carbohydrates Carbohydrates
DNA Replication& Repair DNA Replication & Repair The Central Dogma of molecular biology
RNA & Transcription RNA & Transcription
Protein Synthesis Protein Synthesis
Tools & Techniques for Analyzing DNA DNA analysis
Metabolism & Bioenergetics  
Glucose Metabolism Glucose Metabolism The carbon cycle
The Citric Acid Cycle The Citric Acid Cycle
Oxidative Phosphorylation Oxidative Phosphorylation
Photosynthesis Photosynthesis

A model of the enzyme Cdc14. Red areas have identical amino acid sequences in human and yeast Cdc14. The ideal "key," or substrate, that would fit into Cdc14 is marked by the green and blue structure nestled into a "lock" that is the same in human and yeast Cdc14. (Molecular Cell / Mark Hall)

This structure was determined by Mark Hall, Associate Professor of Biochemistry in the Department of Biochemistry at Purdue University.

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Use CRN: 27331 to register for the course at myPurdue website.


Course at a Glance

4 weeks

20 hours of work per week

Schedule Type: Distance Learning

Instructional Method: Online
(This section is delivered 100% online)

Format: The course is entirely online, and so you can do this course anywhere that you can get access to a reliable internet connection that will allow you to stream film. You do not have to come to campus at all.

Assessments: Assessments will be in the form of quizzes, exams, guided critiques of case studies, literature, and a project. There will be some group work required.

Course Instructor

Orla Hart
Orla Hart

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